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KMID : 0360119950170040317
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Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
1995 Volume.17 No. 4 p.317 ~ p.330
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A study on the effect of Isolated nerve segment on peripheral nerve regeneration using silicone tube
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Abstract
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The purpose of this stud is to observe the stimulant effect of the isolated nerve segment on the peripheral nerve regeneration using silicone tube in rats. Sprague-Dawley female albino rats were used as experimental animals and nerve defects were
made
by resection of 14mm-long segment of right sciatic nerves. In control group, the defects were bridged with the silicone tubes. In experimental group, the defects were bridged with the same manner and additionally, 2mm-long nerve segments were
inserted
at the center of the silicone tubes. 3 months later, the regenerated nerve tissue within the silicone tubes were examined by histologic study. Axonal diameters and numbers of axons were measured and all data were analyzed by using SAS package
program.
@ES The results obtained were as follows :
@EN 1. The experimental group was increased than the control group in general diameters of the regenerated nerve fiber.(P<0.05).
2. The diameters of axons were increased in the experimental group compare to the control group.(P<0.05).
3. The numbers of axons were increased in the experimental group compare to the control group.(P<0.05).
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KEYWORD
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